Blar i forfatter "Suderman, Matthew"

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    • Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study 

      Sun, Yi-Qian; Richmond, Rebecca C.; Suderman, Matthew; Min, Josine L; Battram, Thomas; Flatberg, Arnar; Beisvag, Vidar; Nøst, Therese Haugdahl; Guida, Florence; Jiang, Lin; Wahl, Sissel Gyrid Freim; Langhammer, Arnulf; Skorpen, Frank; Walker, Rosie M; Bretherick, Andrew D; Zeng, Yanni; Chen, Yue; Johansson, Mattias; Sandanger, Torkjel M; Relton, Caroline L; Mai, Xiao-Mei (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      <i>Background</i> - It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated measurements, and to appraise the putative role of DNA methylation in the pathway between smoking and lung cancer development.<br><br> <i>Methods</i> - We derived a nested ...

    • The prognostic ease and difficulty of invasive breast carcinoma 

      Tofigh, Ali; Suderman, Matthew; Paquet, Eric R.; Livingstone, Julie; Bertos, Nicholas; Saleh, Sadiq M.; Zhao, Hong; Souleimanova, Margarita; Cory, Sean; Lesurf, Robert; Shahalizadeh, Solmaz; Garcia Lopez, Norberto; Riazalhosseini, Yasser; Omeroglu, Atilla; Ursini-Siegel, Josie; Park, Morag; Dumeaux, Vanessa; Hallett, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-02)
      Breast carcinoma (BC) has been extensively profiled by high-throughput technologies for over a decade, and broadly speaking, these studies can be grouped into those that seek to identify patient subtypes (studies of heterogeneity) or those that seek to identify gene signatures with prognostic or predictive capacity. The sheer number of reported signatures has led to speculation that everything ...